Vinyltriphenylphosphonium Salt Mediated Serendipitous Synthesis of a Functionalized Pyrroloisoindole Derivative. New Synthesis of Trimethyl 5-Arylpyrrole-2,3,4-tricarboxylates
Abstract
N-Hydroxyphthalimide undergoes a complex reaction with dimethyl acetylenedicarboxylate in the presence of triphenylphosphine yielding a multiply functionalized pyrroloisoindole derivative which is then converted to trimethyl 5-arylpyrrole-2,3,4-tricarboxylate derivatives.