Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 16, 1998
Previous Article Next Article

Enantioselectivity vs. kinetic resolution in antibody catalysis: formation of the (S) product despite preferential binding of the (R) intermediate

Abstract

Antibody 14D9, which catalyzes the stereoselective transformation of achiral enol ethers into the corresponding (S)-ketals, resolves a racemic mixture of structurally similar chiral enol ethers by selective conversion of the (R)-enol ether into the (R)-ketal, raising the possibility that the (S) transition state is preferencially stabilized by the antibody despite a better binding of the (R) intermediate.

Back to tab navigation

Article type: Paper
DOI: 10.1039/A802374C
Citation: Chem. Commun., 1998,0, 1759-1760

  •   Request permissions

    Enantioselectivity vs. kinetic resolution in antibody catalysis: formation of the (S) product despite preferential binding of the (R) intermediate

    D. Shabat, E. Keinan, D. Shabat, H. Shulman, H. Itzhaky and J. Reymond, Chem. Commun., 1998, 0, 1759
    DOI: 10.1039/A802374C

Search articles by author

Spotlight

Advertisements