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Issue 1, 1998
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Total synthesis of rutamycin B via Suzuki macrocyclization

Abstract

The macrolide rutamycin B containing 17 stereogenic centres and a 26-membered ring was synthesized by a route which features a chelate-controlled, double differentiating aldol reaction and ring closure by means of a vinyl–vinyl coupling.

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Article type: Paper
DOI: 10.1039/A707251A
Citation: Chem. Commun., 1998,0, 79-80
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    Total synthesis of rutamycin B via Suzuki macrocyclization

    J. D. White, R. W. Jackson and R. Hanselmann, Chem. Commun., 1998, 0, 79
    DOI: 10.1039/A707251A

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