SCHEDULED MAINTENANCE
Novel 23-, 24- and 28-membered cyclic polyamine amides (cinnamamides) have been prepared by closure of diphenyl ethers; functionalized conjugates of spermidine and spermine underwent intramolecular aromatic nucleophilic substitution to afford nitro-substituted analogues of cadabicine class (24-membered polyamine lactam) alkaloids.
S. Carrington, I. S. Blagbrough and A. H. Fairlamb, Chem. Commun., 1998, 2335 DOI: 10.1039/A806688D
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