A general screening method for enantiomer recognition is introduced for the rapid preparation of novel chiral stationary phases for HPLC in which libraries of mixed chiral selectors are immobilized on polymer beads and the resulting chiral phases tested in the separation of racemic targets followed by deconvolution to afford an optimized separation medium.
P. Murer, K. Lewandowski, F. Svec and J. M. J. Fréchet, Chem. Commun., 1998, 2559 DOI: 10.1039/A806397D
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