Issue 22, 1998

Flavin-oligonucleotide conjugates: sequence specific photocleavage of DNA

Abstract

A flavin–oligonucleotide conjugate forms a stable triple helix with a double-stranded DNA sequence of HIV-1, and selectively photocleaves it at the 3′-G of a GG doublet located 7 bases away from the flavin position.

Article information

Article type
Paper

Chem. Commun., 1998, 2457-2458

Flavin-oligonucleotide conjugates: sequence specific photocleavage of DNA

C. Frier, M. Fontecave, J. Mouscadet, C. Auclair and J. Décout, Chem. Commun., 1998, 2457 DOI: 10.1039/A806119J

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