Issue 21, 1998

Efficient copper (II)-mediated nuclease activity of ortho-quinacridines

Abstract

The ortho-quinacridine compounds OQ1 and OQ2 bind strongly to double stranded DNA and effect efficient cleavage in the presence of Cu2+ and in the absence of reducing agent; their activity increases further in the presence of hydrogen peroxide.

Article information

Article type
Paper

Chem. Commun., 1998, 2349-2350

Efficient copper (II)-mediated nuclease activity of ortho-quinacridines

O. Baudoin, M. Teulade-Fichou, J. Vigneron and J. Lehn, Chem. Commun., 1998, 2349 DOI: 10.1039/A806095I

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