Synthesis of endo,exo-furofuranones using a highly diastereoselective C–H insertion reaction
Abstract
A highly stereoselective ring closure of α-diazo-γ-butyrolactones to form the 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane ring system is reported; a formal synthesis of the furofuran lignan asarinin 1 is also described.