Issue 18, 1998

UV-induced strand break damage in single stranded bromodeoxyuridine-containing DNA oligonucleotides

Abstract

Aerobic UVB photolysis of single stranded bromodeoxyuridine (BrdU)-containing DNA oligonucleotides produces immediate and latent strand break products consistent with a specific BrdU base radical-mediated abstraction of the C1′ hydrogen atom from the 5′ neighbouring deoxyribose.

Article information

Article type
Paper

Chem. Commun., 1998, 1997-1998

UV-induced strand break damage in single stranded bromodeoxyuridine-containing DNA oligonucleotides

Z. A. Doddridge, J. L. Warner, P. M. Cullis and G. D. D. Jones, Chem. Commun., 1998, 1997 DOI: 10.1039/A804416C

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