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Issue 7, 1998
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Synthesis of a novel pseudodisaccharide glycoside as a potential glycosidase inhibitor

Abstract

An N-linked pseudodisaccharide 2 containing an inositol moiety in place of a glycopyranosyl residue has been synthesised to mimic the disaccharide unit, 3-O-(α-D-glucopyranosyl)-D-glucopyranose, cleaved by Glucosidase II during glycoprotein processing; an attempt to prepare the analogous 2-N-linked compound 1 as an inhibitor of Glucosidase I led to the novel N-phenyl derivative 10 of 2-amino-2-deoxy-D-glucopyranose.

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Article information


Chem. Commun., 1998, 817-818
Article type
Paper

Synthesis of a novel pseudodisaccharide glycoside as a potential glycosidase inhibitor

A. H. Haines, Chem. Commun., 1998, 817
DOI: 10.1039/A800279G

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