We demonstrate an amperometric enzyme-linked assay within an ultra-low volume (600 pl) micromachined device for the rapid determination of (hypo)xanthine via a catalytically generated hydrogen peroxide intermediate, thereby illustrating the potential of this technology in a variety of bioanalytical measurements involving the oxidases.
C. D. T. Bratten, J. M. Cooper, C. D. T. Bratten and P. H. Cobbold, Chem. Commun., 1998, 471 DOI: 10.1039/A708233I
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