A tetraphenylporphyrin–peptide hybrid with high affinity for single-stranded DNA
Abstract
A tetraphenylporphyrin bearing four peptide chains, synthesized in two steps from meso-tetrakis- (p-aminophenyl)porphyrin and the peptide CGKWK, binds single-stranded DNA oligomers with high affinity and inhibits degradation by nuclease S1.