Covalently supported porphyrins as ligands for the preparation of heme a3/CuB binuclear active site analogues of heme–copper terminal oxidases and metallation under mild conditions

Abstract

New covalently supported binucleating porphyrins have been prepared as potential structural and/or functional ligands for the iron–copper (heme a₃/Cu_B) active sites of heme–copper oxidases, and the introduction of iron and copper into one porphyrin under mild reaction conditions has been developed.