Issue 21, 1997

Stereoselective synthesis of α-O-fucosylated serine, threonine, tyrosine and saccharides

Abstract

Stereoselective fucosylation of Boc-Ser/Thr/Tyr-OMe 2–4 and several saccharide alcohols 5–7 by coupling with 2-pyridyl tri-O-benzyl-1-thio-β-L-fucosyl donor 1b under iodomethane activation procedure results in the formation of α-linked fucosylated amino acid methyl ester building blocks 8–10 and α-linked fucosyl saccharides 11–13, respectively.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1997, 3179-3182

Stereoselective synthesis of α-O-fucosylated serine, threonine, tyrosine and saccharides

H. Babu Mereyala, S. Reddy Gurrala and R. Reddy Gadikota, J. Chem. Soc., Perkin Trans. 1, 1997, 3179 DOI: 10.1039/A704310D

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