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Issue 5, 1997
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Synthesis of (2R)-2-bromodehydroquinic acid and(2R)-2-fluorodehydroquinicacid


(2R)-2-Bromodehydroquinic acid and (2R)-2-fluorodehydroquinic acid † have each been synthesised in six steps from quinic acid via the common intermediate 6. The syntheses exploit the selective protection of the 4-hydroxy group of the quinic acid lactone 3 with tert-butyldimethylsilyl chloride.

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Article type: Paper
DOI: 10.1039/A606104D
Citation: J. Chem. Soc., Perkin Trans. 1, 1997,0, 625-628
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    Synthesis of (2R)-2-bromodehydroquinic acid and (2R)-2-fluorodehydroquinic acid

    M. K. Manthey, C. González-Bello and C. Abell<img border="0" src="https://www.rsc.org/images/entities/char_200a.gif" alt=" " xmlns="http://www.rsc.org/schema/rscart38" />, J. Chem. Soc., Perkin Trans. 1, 1997, 0, 625
    DOI: 10.1039/A606104D

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