Issue 9, 1997

Synthesis based on cyclohexadienes. Part 22.1 Formal syntheses of patchouli alcohol and norpatchoulenol

Abstract

The preparation of 6-endo-formyl-1,3,3-trimethylbicyclo[2.2.2]octan-2-one 7 and 6-endo-acetyl-1,3,3-trimethylbicyclo[2.2.2]octan-2-one 8, the two key intermediates for the synthesis of patchouli alcohol 1 and norpatchoulenol 2, is reported by a simple and short method from 2-methylbenzoic acid.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1997, 1385-1390

Synthesis based on cyclohexadienes. Part 22.1 Formal syntheses of patchouli alcohol and norpatchoulenol

K. P. Kaliappan and G. S. R. Subba Rao, J. Chem. Soc., Perkin Trans. 1, 1997, 1385 DOI: 10.1039/A607286K

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