Novel synthesis of 10-membered cyclic bis-ethers from 4-(N-alkylanilino)but-2-yn-1-ols 1

Abstract

A number of symmetrical 10-membered cyclic bis-ethers 5a–f are synthesized in a single step in good yields from the reaction of 4-(N-alkylanilino)but-2-yn-1-ols 3a–f with m-chloroperbenzoic acid in dichloromethane at room temperature during 8 h.