Jump to main content
Jump to site search

Issue 4, 1997
Previous Article Next Article

Preparation, structure, derivatisation and NMR data of cyclohexane-1,2-diacetal protected carbohydrates

Abstract

Acid catalysed reaction of monosaccharides with 1,1,2,2-tetramethoxycyclohexane results in selective protection of vicinal, diequatorial, diol functionality as a cyclohexane-1,2-diacetal (CDA). This new methodology complements classical cyclic acetal protecting group strategies which in general are not able to mask diols with such diequatorial stereochemistry. The resulting CDA protected derivatives can be readily functionalised to give rapid access to numerous key building blocks for oligosaccharide and natural product synthesis.

Back to tab navigation

Article information


J. Chem. Soc., Perkin Trans. 1, 1997, 351-364
Article type
Paper

Preparation, structure, derivatisation and NMR data of cyclohexane-1,2-diacetal protected carbohydrates

P. Grice, S. V. Ley, J. Pietruszka, H. W. M. Priepke and S. L. Warriner, J. Chem. Soc., Perkin Trans. 1, 1997, 351
DOI: 10.1039/A605851E

Search articles by author

Spotlight

Advertisements