Reaction of Isoeugenol with Formaldehyde in Basic Medium: Formation of trans-4-(4-Hydroxy-3-hydroxymethyl-5-methoxy)-5-methyl-1,3-dioxane and its Transformation into the Tricyclo[5.2.2.02,6]undecane System†
Abstract
Formation of the title compound 3, via an unusual Prins-type reaction on isoeugenol with formaldehyde in alkaline medium, and its conversion into a tricyclo[5.2.2.02,6]undecane system 4 is described.