A Convenient Route to 3,6-Diaminofluoren-9-ones

Abstract

The synthesis of fluoren-9-ones having a 3,6-bis(tertiary amino) functionality is described, in which the amino groups are introduced using either cyclic secondary amines or their N-formylated derivatives to effect nucleophilic displacement of the halogen from 3,6-dichlorofluoren-9-one, which is derived from 4-chloroanthranilic acid.