Issue 2, 1997

Synthesis of Enantiopure 4-Amino-6-fluoro- 3-(hydroxymethyl)chromanes via Intramolecular Nitrone Cycloadditions

Abstract

Enantiopure 4-amino-6-fluoro-3-(hydroxymethyl)chromanes are synthesised starting from 5-fluorosalicylaldehyde and using (R)-(+)-(1-phenylethyl)hydroxylamine as chiral auxiliary.

Article information

Article type
Paper

J. Chem. Res. (S), 1997, 36-37

Synthesis of Enantiopure 4-Amino-6-fluoro- 3-(hydroxymethyl)chromanes via Intramolecular Nitrone Cycloadditions

G. Broggini, E. Cappelletti, G. Zecchi and L. Bruché, J. Chem. Res. (S), 1997, 36 DOI: 10.1039/A606616J

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