Issue 3, 1997

Complexation of transition-metal ions, SnII, PbII and Al III with nucleobase-substituted polyethers and dissociation of adduct ions studied by fast atom bombardment mass spectrometry

Abstract

Metal-ion-complexed dinucleotide analogues were studied by FAB mass spectrometry using tri- and bi-valent transition-metal ions (Cr to Zn), Sn II , Pb II and Al III . Pairs of thymine nucleobases linked by (CH 2 ) 2 - [O(CH 2 ) 2 ] n O(CH 2 ) 2 chains (n = 1 1, 2 2, 3 3 or 4 4) and of adenine nucleobases (n = 1 5 or 4 6) co-ordinate to metal ions and form significant [M + M - H] + and [M + MCl] + ions. In addition, many transition-metal ions also give [M + M 2 X - 2H] (X = Cl or NO 3 ) ions but Cr III produces [M + CrCl 2 ] + ions. The effect of the spacer chain length is reflected in the ease of formation of [M + M - H] + and [M + MX] + ions. Fragmentation of [M + MX] + and [M + M 2 X - 2H] ions give [M + M - H] + ions, suggesting that metal chelation through the nucleobase is more favoured than through the polyether. Complexes of compounds 16 with Al III –glycerol give abundant [M + 117] + complex ions (117 = Al + glycerol - 2H). The intensities of these ions decrease with increasing number of ethylene oxide units from 14. The same trend is also observed in 5 and 6. Bimetallic ions with an unipositive charge are also produced from 14. Dissociation of adduct ions labelled with deuterium confirms the substitution of amide protons with aluminium(III) in the elimination of glycerol.

Article information

Article type
Paper

J. Chem. Soc., Dalton Trans., 1997, 341-346

Complexation of transition-metal ions, SnII, PbII and Al III with nucleobase-substituted polyethers and dissociation of adduct ions studied by fast atom bombardment mass spectrometry

M. Saraswathi and J. M. Miller, J. Chem. Soc., Dalton Trans., 1997, 341 DOI: 10.1039/A605354H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements