Issue 22, 1997

A simple construction of chiral fused benzoxocine ring ethers from D-glucose by regioselective 8-endo-aryl radical cyclisation

Abstract

A regioselective 8-endo-trig aryl radical cyclisation of the 5,6-deoxy-D-xylo-5-enofuranosides 3a and 3b with tri-n-butyltin hydride provides the chiral furo[3,2-c][2]benzoxocines 4a and 4b in good yields; the crystal structure of 4a is reported.

Article information

Article type
Paper

Chem. Commun., 1997, 2139-2140

A simple construction of chiral fused benzoxocine ring ethers from D-glucose by regioselective 8-endo-aryl radical cyclisation

P. Chattopadhyay, M. Mukherjee and S. Ghosh, Chem. Commun., 1997, 2139 DOI: 10.1039/A706249D

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