Construction of the tricyclo[5.3.1.01,5]undecane system by a tandem pinacol rearrangement–ene strategy: a formal synthesis of (±)-perhydrohistrionicotoxin
Abstract
An advanced synthetic intermediate 4 for perhydrohistrionicotoxin 5 has been synthesized utilizing a novel tandem pinacol rearrangement–ene reaction as a key step.