A method for gaining access to 2-alkyl-3-phenyl-substituted tropanes using the chiral dipolarophile (R)-p-tolyl vinyl sulfoxide in the asymmetric 1,3-dipolar cycloaddition reaction with the oxidopyridinium betaine 4 is described.
G. Luca Araldi, K. R. C. Prakash, A. P. Kozikowski, G. Luca Araldi and C. George, Chem. Commun., 1997, 1875 DOI: 10.1039/A704216G
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