New chiral ammonium salt hosts derived from amino acids: very efficient optical resolution of 2,2′-dihydroxy-1,1′-binaphthyl by complexation with these host compounds

Abstract

Chiral ammonium salt hosts are prepared from amino acids by transformation of their NH ₂ and CO ₂ H groups into Me ₃ N ⁺ Br ^- and CH ₂ OH groups, respectively, via three simple reaction steps; by complexation with these hosts, 2,2′-dihydroxy-1,1′-binaphthyl is resolved very efficiently.