Analysis of Phenols in Water at the ppb Level Using Direct Supercritical Fluid Extraction of Aqueous Samples Combined On-line With Supercritical Fluid Chromatography–Mass Spectrometry

Abstract

A high pressure multivalve switching system has provided a means of interfacing a direct aqueous SFE vessel to a packed column SFC-MS system. Using full scan negative ion atmospheric pressure chemical ionization, the combined SFE–SFC–MS instrumentation enabled the analysis of phenols in water at the 40 ppb level.