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Issue 17, 1996
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Coupling of ribofuranosyl fluoride and indoles


The coupling reaction of a D-ribofuranosyl fluoride with indoles in the presence of boron trifluoride gives the corresponding C-nucleosides in a stereoselective manner depending upon reaction temperatures and solvents: the β-anomer is preferred under such conditions as –15 to –40 °C in nitroethane while the α-anomer is preferred at –78 °C in propiononitrile.

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Article type: Paper
DOI: 10.1039/P19960002145
Citation: J. Chem. Soc., Perkin Trans. 1, 1996,0, 2145-2149

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    Coupling of ribofuranosyl fluoride and indoles

    M. Yokoyama, M. Nomura, H. Togo and H. Seki, J. Chem. Soc., Perkin Trans. 1, 1996, 0, 2145
    DOI: 10.1039/P19960002145

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