Issue 8, 1996
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Synthesis of Nπ-2-adamantyloxymethylhistidine, his(Nπ-2-adom), and its evaluation for peptide synthesis

Yoshio Okada,   Jidong Wang,   Takeshi Yamamoto  and  Yu Mu  

Abstract

N π -2-Adamantyloxymethylhistidine, His(Nπ-2-Adom), is prepared and successfully applied to the synthesis of thyrotropin-releasing hormone (TRH) in combination with tert-butyloxycarbonyl (Boc) as the Nπ-protecting group. This new protecting group suppressed racemization during peptide synthesis and exhibited high solubility in organic solvents.

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Article information

DOI
https://doi.org/10.1039/P19960000753
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1996, 753-754

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Synthesis of Nπ-2-adamantyloxymethylhistidine, his(Nπ-2-adom), and its evaluation for peptide synthesis

Y. Okada, J. Wang, T. Yamamoto and Y. Mu, J. Chem. Soc., Perkin Trans. 1, 1996, 753 DOI: 10.1039/P19960000753

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