Issue 2, 1996

An asymmetric total synthesis of (+)-(3R,4S,5R,7S)-neoclausenamide

Abstract

A new hepatoprotective lactam (+)-(3R,4S,5R,7S)-neoclausenamide 1 isolated from the leaves of Chinese folk medicine Clausena lansium(Lour.) Skeel, has been readily synthesized from methyl (2R,3S)-2,3-dihydroxy-3-phenylpropanoate in 22.0% overall yield.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1996, 209-212

An asymmetric total synthesis of (+)-(3R,4S,5R,7S)-neoclausenamide

J. Wang and W. Tian, J. Chem. Soc., Perkin Trans. 1, 1996, 209 DOI: 10.1039/P19960000209

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