By increasing the number of thiazole units in the photoactive DNA cleaving compounds, 4-(3-dimethylsulfoniopropyl-aminocarbonyl)-2-[2-(4-nitrobenzoylamino)ethyl] oligo- thiazole, from one or two to three, the specificity of their DNA cleavage was dramatically altered from 5′-AAATN-3′(N ≠ G) to 5′-GG-3′.
K. Ninomiya, H. Satoh, T. Sugiyama, M. Shinomiya and R. Kuroda, Chem. Commun., 1996, 1825 DOI: 10.1039/CC9960001825
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