Intramolecular reaction of γ-alkoxyallylstannane with hydrazone: stereoselective synthesis of β-aminotetrahydro-pyran and-furan
Abstract
The Lewis acid mediated cyclization of β-oxygen substituted allylic stannanes 1,2, and 9, bearing a hydrazone group at the terminus of the carbon chain, afforded the corresponding trans-β-amino cyclic ethers 3a,4a and 10, respectively, with very high diastereoselectivities in high chemical yields.