Issue 5, 1996

Enantioselective addition of diethylzinc to aldehydes catalysed by a β-amino disulfide derived from L-proline

Abstract

A novel β-amino disulfide 2 is prepared and is effective at catalytic levels (1.25–2.5 mol%) in the enantioselective addition of diethylzinc to aldehydes providing (R)-secondary alcohols in up to 99% ee.

Article information

Article type
Paper

Chem. Commun., 1996, 645-646

Enantioselective addition of diethylzinc to aldehydes catalysed by a β-amino disulfide derived from L-proline

C. L. Gibson, Chem. Commun., 1996, 645 DOI: 10.1039/CC9960000645

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