Issue 3, 1996

A new route for the synthesis of pyrrolo[2,1-c][1,4]benzodiazepine antibiotics via oxidation of cyclic secondary amine

Abstract

The synthesis of the imine-containing pyrrolo[2,1-c][1,4]benzodiazepine DNA–binding antitumour antibiotics was achieved by a new method of oxidation of cyclic secondary amines which does not endanger the stereochemical integrity of the C-11a position.

Article information

Article type
Paper

Chem. Commun., 1996, 385-386

A new route for the synthesis of pyrrolo[2,1-c][1,4]benzodiazepine antibiotics via oxidation of cyclic secondary amine

A. Kamal and N. V. Rao, Chem. Commun., 1996, 385 DOI: 10.1039/CC9960000385

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