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Issue 1, 1996
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Existence of two basic sites in triazolo-1,4-diazepines: determination of two pKa values for a model compound in water

Abstract

By a UV/VIS spectrophotometric study in the pH range –1.6 to 10.1 and by a polarographic study of a water soluble model compound, the occurrence of two basic sites in water has been ascertained for triazolo-1,4-diazepines. The pKa values found for this model were –0.24 and +1.81. Owing to the overlapping of the two pKa values, microforms exist simultaneously. Corresponding ionization microconstant values have been tentatively assigned.

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Article type: Paper
DOI: 10.1039/AN9962100043
Analyst, 1996,121, 43-48

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    Existence of two basic sites in triazolo-1,4-diazepines: determination of two pKa values for a model compound in water

    B. Legouin and J. Burgot, Analyst, 1996, 121, 43
    DOI: 10.1039/AN9962100043

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