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Issue 14, 1995
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Titanium(IV) mediated reductive aminations of 1-adamantyl methyl ketone: facile preparation of potential antiviral agents rimantadine and its analogues

Abstract

A preparatively efficient, mild method for the synthesis of rimantadine and its analogues via novel reductive aminations of 1-adamantyl methyl ketone using titanium(IV) isopropoxide and sodium borohydride is reported.

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Article type: Paper
DOI: 10.1039/P19950001845
Citation: J. Chem. Soc., Perkin Trans. 1, 1995,0, 1845-1847
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    Titanium(IV) mediated reductive aminations of 1-adamantyl methyl ketone: facile preparation of potential antiviral agents rimantadine and its analogues

    S. Bhattacharyya, J. Chem. Soc., Perkin Trans. 1, 1995, 0, 1845
    DOI: 10.1039/P19950001845

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