Diethyl trichloromethylphosphonate 1 and chlorotrimethylsilane were converted in a three-step sequence by BuLi into α-phosphorylated α-silylated α-substituted carbanions 4. These, on reaction with ethyl formate in the presence of chlorotrimethylsilane give transient silylated acetals 8 which readily undergo acid hydrolysis to afford 1-formylalkylphosphonates 7 in good yield.
Y. Zanella, S. Berté-Verrando, R. Dizière and P. Savignac, J. Chem. Soc., Perkin Trans. 1, 1995, 2835 DOI: 10.1039/P19950002835
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