Acylnitrilium ion initiated spiroannulations in heterocycle synthesis: an application directed toward the total synthesis of the Lycopodium alkaloid (±)-serratine
Abstract
A concise synthesis of a prospective tricyclic intermediate en route to the Lycopodium alkaloid (±)-serratine is described which involves the consecutive utilization of an acylnitrilium ion initiated spiroannulation and intramolecular Michael addition.