Reaction of ortho-lithiated protected anilines with o-hydroxycarbonyl compounds: formation of quino- and pyranoquino-acridines
Abstract
Reaction of N-tert-butoxycarbonyl-2-lithioaniline and p-anisidine with 1-hydroxy-3-methoxy-10-methyl-acridone and noracronycine gave quino[2,3,4-kl]acridines and pyrano[3,2-b]quino[4,3,2-mn]acridines respectively, which are related to biologically active compounds recently isolated from various marine animals.