A series of uridine derivatives have been prepared with a view to inhibiting the enzyme ribonucleotide reductase by trapping the radical responsible for initiating the reduction. These have an oxime ether on the beta face at C-3 or C-2 of the ribose moiety.
S. P. Auguste and D. W. Young, J. Chem. Soc., Perkin Trans. 1, 1995, 395 DOI: 10.1039/P19950000395
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