Issue 3, 1995

Novel preparation of 3-alkyl-5-hydroxy-5-per(poly)fluoroalkyl-4,5-dihydroisoxazoles

Abstract

3-Alkyl-5-hydroxy-5-per(poly)fluoroalkyl-4,5-dihydroisoxazoles have been synthesized by a 1,3-dipolar cycloaddition of trimethylsilyl nitronates to 1-bromo-1-per(poly)fluoroalkylethene via a one-pot or two-step reaction. The reaction was regiospecific and an intermediate containing the trimethylsiloxy group has been isolated.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1995, 267-269

Novel preparation of 3-alkyl-5-hydroxy-5-per(poly)fluoroalkyl-4,5-dihydroisoxazoles

J. Chen and C. Hu, J. Chem. Soc., Perkin Trans. 1, 1995, 267 DOI: 10.1039/P19950000267

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