Issue 1, 1995

Improved synthesis of isoguanosine and 6-substituted xanthosine derivatives

Abstract

Isoguanosine 1 was obtained in 76% overall yield starting from 2′,3′,5′-tri-O-acetylxanthosine 3 in a reaction involving the chloro derivative 4 and the N-(purin-6-yl)pyridinium salt derivative 8 which also proved to be new and valuable synthetic intermediates in the obtainment of C-6-substituted xanthosine derivatives.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1995, 15-17

Improved synthesis of isoguanosine and 6-substituted xanthosine derivatives

L. De Napoli, D. Montesarchio, G. Piccialli, C. Santacroce and M. Varra, J. Chem. Soc., Perkin Trans. 1, 1995, 15 DOI: 10.1039/P19950000015

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