Issue 23, 1995

The scope and mechanism of a novel synthesis of 3,4-fused isoxazoles

Abstract

Thermal cyclisation of 2-nitrophenyl- and 3-nitrohetaryl-ethanoate derivatives in xylene is facilitated indirectly by 5 Å molecular sieves affording an efficient general method for the construction of synthetically useful 3,4-fused isoxazoles; evidence for the mechanism of these novel heterocyclisation reactions is presented.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1995, 2457-2459

The scope and mechanism of a novel synthesis of 3,4-fused isoxazoles

K. J. Duffy and G. Tennant, J. Chem. Soc., Chem. Commun., 1995, 2457 DOI: 10.1039/C39950002457

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