Deoxycholic acid micelles have been used successfully in capillary electrophoresis to estimate the octanol-water partition coefficient (log P) of a number of drugs; the methodology developed is fast and is suitable for the determination of this physico-chemical parameter for neutral, basic and weakly acidic molecules with a variety of structures.
M. Adlard, G. Okafo, E. Meenan and P. Camilleri, J. Chem. Soc., Chem. Commun., 1995, 2241 DOI: 10.1039/C39950002241
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