The alkaloid melinonine-E has been synthesised for the first time, the key steps being the elaboration of the 2-azabicyclo[3.3.l]nonane nucleus by a radical cyclisation, the epimerisation of the cyano group to an axial position, and the closure of the C ring by Bischler–Napieralski cyclisation.
J. Quirante, C. Escolano, J. Bosch and J. Bonjoch, J. Chem. Soc., Chem. Commun., 1995, 2141 DOI: 10.1039/C39950002141
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...