Issue 17, 1995

Facile formation of a cis-platin-nonapeptide complex of human DNA polymerase-α origin

Abstract

cis-DDP readily forms a complex with a nonapeptide, E R F K C P C P T, selected from near the DNA binding domain of human DNA polymerase-α, through the two cysteine residues; the reaction is more than an order of magnitude faster than that for the cis-DDP and DNA reaction.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1995, 1731-1732

Facile formation of a cis-platin-nonapeptide complex of human DNA polymerase-α origin

R. N. Bose, D. Li, M. Kennedy and S. Basu, J. Chem. Soc., Chem. Commun., 1995, 1731 DOI: 10.1039/C39950001731

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