An efficient, scalable route to the Taxol A-ring synthon is described; high stereoseiectivity and regioselectivity are achieved by means of an intermolecular Aldol addition and an intramolecular Aldol condensation.
Y. Ding and X. Jiang, J. Chem. Soc., Chem. Commun., 1995, 1693 DOI: 10.1039/C39950001693
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