Phenanthridine-linked hydroxamic acid 1 effectively cleaves ColE1 DNA in the presence of transition (ferrous, ferric and vanadyl) or lanthanide(III)(lutetium, thulium and europium) metal ions; in the presence of the former, the cleavage is inhibited by free radical scavengers, but in the latter case it is not.
S. Hashimoto and Y. Nakamura, J. Chem. Soc., Chem. Commun., 1995, 1413 DOI: 10.1039/C39950001413
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