Issue 4, 1995

Approaches to the assembly of the antifungal agent FR-900848: studies on the synthesis of C2 symmetric tetracyclopropane derivatives and an X-ray crystallographic study of (1R,3S,4S,6R)-bicyclopropyl-1,6-di-{2-[(4R,5R)-di-(isopropyloxycarbonyl)-1,3-dioxolane]}

Abstract

Two sequential asymmetric bicyclopropanation reactions were used to prepare (1R,3S,4R,6S,7S,9R,10S,12R)-quatercyclopropyl-1,12-dimethanol and (1S,3R,4R,6S,7S,9R,10R,12S)-quatercyclopropyl-1,12-dimethanol.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1995, 407-408

Approaches to the assembly of the antifungal agent FR-900848: studies on the synthesis of C2 symmetric tetracyclopropane derivatives and an X-ray crystallographic study of (1R,3S,4S,6R)-bicyclopropyl-1,6-di-{2-[(4R,5R)-di-(isopropyloxycarbonyl)-1,3-dioxolane]}

A. G. M. Barrett, W. W. Doubleday, K. Kasdorf, G. J. Tustin, A. J. P. White and D. J. Williams, J. Chem. Soc., Chem. Commun., 1995, 407 DOI: 10.1039/C39950000407

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