A conjugate addition—radical cyclisation approach to sesquiterpene phenols
Abstract
A polycyclic ring system consisting of fused sesquiterpene and phenolic units, whose structure was found by X-ray crystallography to coincide with that which forms the nucleus of a series of natural products, can be constructed from chromone and terpene precursors via sequential conjugate addition and manganese(III)-induced 6-endo-trig radical cyclisation reactions.